Symbol
Name
ID

Shoc2
Shoc2, leucine rich repeat scaffold protein
MGI:1927197

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Conjunctivitis	Atrial septal defect	Ventricular septal defect	Hypertrophic cardiomyopathy	Aortic regurgitation	Pulmonic stenosis	Hemangioma	Facial erythema
Disease(s) Associated with SHOC2	Conjunctivitis	Atrial septal defect	Ventricular septal defect	Hypertrophic cardiomyopathy	Aortic regurgitation	Pulmonic stenosis	Hemangioma	Facial erythema
atopic dermatitis
Noonan syndrome-like disorder with loose anagen hair 1

Mouse Phenotypes

cardiovascular system phenotype

right aortic arch

pulmonary vascular congestion

abnormal cardiovascular development

abnormal cardiac epithelial to mesenchymal transition

decreased atrioventricular cushion size

abnormal atrioventricular valve development

abnormal semilunar valve development

double outlet right ventricle

transposition of great arteries

ventricular septal defect

hemorrhage

Availability

Mouse Genotype

Shoc2^tm1.1Mhan/Shoc2^tm1.2Mhan
Tg(Tek-cre)#Xya/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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